Laboratory of Molecular Epidemiology of Viral Infections

Head of the laboratory  - Doctor of BiologicalSciences (DSci. in Biology), Professor, Merited worker of health services of the Russian Federation

Nadezhda A.Novikova

The laboratory of Molecular Epidemiology of Viral Infections was established in 1992. Currently, the Volga regional scientific and methodological center for the study of enterovirus infections has been operating on the basis of the laboratory since 2007 and the reference center for the monitoring of enterovirus infections since 2008.

Directions of activities:

• Studying genetic and antigenic diversity and molecular evolution of viruses of the intestinal group and internal mechanisms of the development of the epidemic process of diseases caused by them.

Laboratory achievements:

• The laboratory methods for the detection and genotyping of intestinal viruses protected by copyright certificates and patents have been developed.
• The molecular genetic characteristics of modern epidemically significant strains of rotaviruses of group A, noroviruses and enteroviruses have been given.
• Based on the analysis of the established nucleotide sequences of the genome fragments of enteroviruses identified on the territoryof 54 subjects of 8 federal districts of the Russian Federation, the landscape of non-polio enteroviruses, represented by 52 types, has been characterized.
• For the first time, the wide circulation of human parechoviruses among the population of Russia is shown, their type and genetic diversity has been studied.

Prospects

• In-depth molecular genetic characterization of known and new enteral viruses using whole genome sequencing.
• Studying the pathogenicity determinants of the enteric viruses, the evolution of the genome and antigenic properties.

Phone: +7(831) 469-79-12 Nadezhda A.Novikova

E-mail: mevirfc@rambler.ru

Address: 603950, Nizhny Novgorod, Malaya Yamskaya st., 71, 3th floor.

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