02 12.2024

Nikolay Semashko: the creator of Soviet healthcare

The Soviet healthcare system was considered one of the best in the world. Its uniqueness lay in the unified principles of organization and centralization of all healthcare, and the key role was played by free of charge, accessibility and qualification. The creator of the model was Nikolai Aleksandrovich Semashko, the first People's Commissar of Health of the Soviet Union.

27 11.2024

World AIDS Day

World AIDS Day, declared in 1988, was the first internationally recognized day dedicated to health protection. Its purpose is to raise global awareness of HIV/AIDS, provide support to people living with HIV, and unite efforts to combat the spread of this disease.

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Important publications

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Belova, I. V. Analysis of Changes in the Intestinal Microbiota of Patients with Infectious and Somatic Pathology / I. V. Belova, A. G. Tochilina, I. V. Soloveva, S. B. Molodtsova, D. B. Gelashvili, V. S. Kropotov // Opera Medica et Physiologica. – 2024. – V. 11, No 3. – P. 67–92.
Tochilina, A.G. Results of the study of biological and molecular genetic properties of Bifidobacterium strains – probiotic producers / A.G. Tochilina, I.V. Belova, I.V. Soloveva, T.N. Ilyicheva, D.B Gelashvili., V.A. Zhirnov, S.B. Molodtsova // Opera Medica et Physiologica. – 2023. – V. 10, No 1. – P. 72–105.
Perfilova, K.M. Macrolide resistance of H.pylori due to ermB gene during H. pylori infection in real practice / K.M. Perfilova, T.Yu. Butina, N.V. Neumoina, I.V. Shutova, I.A. Kuznetsova, T.A. Troshina, T.V. Shmakova, S.N. Levina // OM&P. – 2024. – V. 11, Issue 2. – P. 129–138.
Boriskina, O.S. Bronchial asthma and bilirubin / O.S. Boriskina, T.I. Eliseeva, E.V. Tush, S.K. Soodaeva, R.N. Khramova, E.A. Khristianovich, E.V. Pavlova, V.V. Novikov, A.I. Khaletskaya, V.A. Bulgakova, N.Sh. Kurmaeva, N.I. Kubysheva // Opera Medica et Physiologica. – 2024. – V. 11, No 1. – Р. 115–122.
Novikov, D. V.Prospects for the use of viral proteins for the construction of chimeric тoxins / D. V. Novikov, E. A. Vasilchikova, P. I. Vasilchikov // Archives of Virology. – 2024. – V. 169, No 10. – P. 208.
Novikov, D. V. CD38 gene polymorphism rs1130169 contribution to the increased gene expression and risk of colorectal cancer (pilot study) / D. V. Novikov, A. D. Perenkov, S. V. Shumilova, N. I. Kubysheva, V. V. Novikov // Molecular Biology Reports. – 2024. – V. 51, No 1. – Р. 63.
Pleskova, S. N. Pathogenic Escherichia coli change the adhesion between neutrophils and endotheliocytes in the experimental bacteremia model / S. N. Pleskova, N. A. Bezrukov, S. Z. Bobyk, E. N. Gorshkova, D. V. Novikov // Microb. Cell. – 2024. – V. 11, No 1. – P. 254–264.
Chammartin, F. Measures of longitudinal immune dysfunction and risk of AIDS and non-AIDS defining malignancies in antiretroviral-treated people with human immunodeficiency virus / Chammartin F., Mocroft A., Egle A., … Kuzovatova Е., [et al.] // Clinical Infectious Diseases. – 2024. – V. 78, No 4. – P. 995–1004.
Filatova, E.N. Detection of H. influenzae in samples from patients with community-acquired pneumonia using a DNA microarray / E.N. Filatova, N.A. Sakharnov, N.F. Brusnigina, M.A. Makhova, O.V. Utkin // Opera Medica et Physiologica. - 2024. - V.11, Issue 2. - P. 148-158.
Talayev, V. CCR6+ T helper cells and regulatory T cells in the blood and gastric mucosa during Helicobacter pylori infection / V. Talayev, M. Svetlova, I. Zaichenko, E. Voronina, O. Babaykina, N. Neumoina, K. Perfilova // Helicobacter. – 2024. - V.29. - No 3. - e13097.
Vaks, V. L. Application of High-Resolution Terahertz Spectroscopy for Studying Biofilms Typical of ENT Pathologies / V. L. Vaks, A. A. Aizenshtadt, V. A. Anfertev [et al.] // Radiophysics and Quantum Electronics. – 2023. – V. 66, No. 7-8. – P. 610–617.
Sashina, T.A. Detection and full-genotype determination of rare and reassortant rotavirus A strains in Nizhny Novgorod in the European part of Russia / T.A. Sashina, E.I. Velikzhanina, O.V. Morozova, N.V. Epifanova, N.A. Novikova // Archives of Virology. – 2023. – V. 168, No 8. – P. 215.
Romanenkova, N.I. Enterovirus 71-Associated Infection in South Vietnam: Vaccination Is a Real Solution / N.I. Romanenkova, T.T.T. Nguyen, L.N. Golitsyna, N.V. Ponomareva, N.R. Rozaeva, O.I. Kanaeva, A.V. Leonov , N.A. Novikova, M.A. Bichurina // Vaccines (Basel). – 2023. – V. 11, No 5. – P. 931.
Álvarez, H. Plasma human immunodeficiency virus 1 RNA and CD4+ T-cell counts are determinants of virological nonsuppression outcomes with initial integrase inhibitor-based regimens: a prospective respond cohort study / H. Álvarez, A. Mocroft, L. Ryom, … Kuzovatova Е., [et al.] // Clinical Infectious Diseases. – 2023. – V. 77, No 4. – P. 593–605.
Greenberg, L. Trends in cancer incidence in different antiretroviral treatment-eras amongst people with HIV / L. Greenberg, L. Ryom, E. Bakowska,… Kuzovatova Е., [et al.] // Cancers. – 2023. – V. 15, No 14. – P. 3640.
Zharova, A.-M.D. In silico analysis of the antigenic properties of norovirus GII.4 Sydney [P16] VP1 protein / A.-M.D. Zharova, V.Yu. Talayev, A.D. Perenkov, I.Ye. Zaichenko, M.V. Svetlova, O.N. Babaykina, E.V. Voronina, V.A. Lapin, V.V. Novikov // Opera Medica et Physiologica. – 2023. – V. 10. – No 3. – P. 140-151.
Filatova, E.N. Experience in modeling and predicting the incidence of community-acquired pneumonia during the COVID-19 pandemic / E.N. Filatova, M.I. Popkova, N.N. Zaitseva, O.V. Utkin // Opera Medica et Physiologica. - 2023. - V.10, Issue 4. - P. 132-142.
Amele, S. HCV reinfection after HCV therapy among HIV/HCV-coinfected individuals in Europe / S. Amele, A.K. Sandri, A. Rodger,… Kuzovatova Е., [et al.] // HIV Medicine. – 2022. – V. 23, No 6. – P. 684–692.
Kolesnikova, E.A.Molecular-genetic characteristics of M. hominis clinical isolates efflux systems / E.A. Kolesnikova, N.F. Brusnigina, M.A. Makhova, A.E. Alekseeva, E.V. Pligina // Opera Medica et Physiologica. – 2022. – Vol.9, № 1. – P. 5-12.
Peksheva, O. Prevalence and Structure of HIV-1 Drug Resistance to Antiretrovirals in the Volga Federal District in 2008–2019. Peksheva, O.; Kuzovatova, E.; Parfenova, O.; Zaytseva, N. // Viruses. - 2022. - Vol. 1. - P. 1898
Epifanova, N.V. An increase in prevalence of recombinant GII.3[P12] norovirus in sporadic acute diarrhea in children in Nizhny Novgorod, Russia, 2018–2021 / N.V. Epifanova, T.A. Sashina, O.V. Morozova, [et al.] // Virus Genes. – 2022. – V. 58. – No 5. – P. 467–472.
Vu, Т.L. Study of the genetic diversity of enteroviruses circulating in the Socialist Republic of Vietnam / Т.L. Vu, N.I. Romanenkova, Т.М. Luong, [et al.] // Journal of Tropical Science and Technology (Hanoi). – 2022. – No 26. – P. 110–117.
Oparina, S.V. Phylogenetic analysis of noroviruses based on RNA-dependent RNA polymerase GII.P16 gene sequences / S.V. Oparina, N.V. Epifanova, N.A. Novikova // Opera Med Physiol. 2022. – V. 9. – No 3. – P. 87–97.
Ivanova, O.E. Cases of acute flaccid paralysis associated with Coxsackievirus A2: findings of a 20-year surveillance in the Russian Federation / O. E. Ivanova, A. K. Shakaryan, N. S. Morozova, [et al.] // Microorganisms. – 2022. – V. 10. Iss. 1. – P. 112.
Khrulev, A.E. Specific Cerebrovascular Risk Factors, Colon Microbiocenosis and Its Correction in Patients Receiving Long-Term Programmed Hemodialysis / A.E. Khrulev, I.V. Belova, I.V. Solovyeva, A.G. Tochilina, N.A. Shiyanova, A.A. Nikitina, N.S. Khruleva // Multidisciplinary Experiences in Renal Replacement Therapy. - London. - IntechOpen. - 2021. - 10.5772/intechopen.101300.
Gazhva, S. A combination treatment for chronic periodontitis associated with dysbiosis of oral microbiota and assessment of its effectiveness / S. Gazhva, Yu. Ibragimova, V. Ryabova, Yu. Gazhva, I. Belova, A. Tochilina, I. Solovyeva, V. Aivazyan, N. Abdullaev // Archiv euromedica. - 2022. - Vol.12, №1. - P. 77-83.
Lapshtaeva, A.V. Predictors of adverse outcome of in vitro fertilization programs / A.V. Lapshtaeva, I.V. Sychev, A.I. Adamchik, et al. // Gynecology, Obstetrics and Perinatology. – 2021. – V. 20. – No 1. – P. 22–28.
Morozova, O.V. Increasing detection of rotavirus G2P[4] strains in Nizhny Novgorod, Russia, between 2016 and 2019 / O.V. Morozova, T.A. Sashina, N.V. Epifanova, et al. // Archives of Virology. – 2021. – V. 166. – No 1. – P. 115–124.
Nosenko, M. A. Generation and Evaluation of Bispecific Anti-TNF Antibodies Based on Single-Chain V H H Domains / M. A. Nosenko, K.-S. N. Atretkhany, V. V. Mokhonov, et al. // Methods in Molеcular Biology. – 2021. – V. 2248. – P. 91–107.
Novikov, V. V. The role of soluble molecules CD25, CD38, CD95 in the development of immunosuppression in cytomegalovirus infection / V. V. Novikov, G. A. Kravchenko, D. M Sobchak, et al. // ЗНИСО. – 2021. – №4(337). – С. 74–78.
Soloveva, I. V. Genome Features and In Vitro Activity against Influenza A and SARS- CoV-2 Viruses of Six Probiotic Strains / I. V. Soloveva, T. N. Ilyicheva, V. Yu. Marchenko, et al. // BioMed Research International. – 2021. – V. 2021. – ID 6662027, 11 p.
Alekseeva, A.E. The mobilome of carbapenem-resistant Klebsiella pneumoniae clinical isolates / A.E. Alekseeva, N.F. Brusnigina, N.A. Gordinskaya // Russian Journal of Genetics. – 2020. – V. 56. – No 3. – P. 280–288.
Drutskaya, M.S. Effects of myeloid cell-restricted TNF inhibitors in vitro and in vivo / M.S. Drutskaya, M.A. Nosenko., E.A. Gorshkova, et al. // Journal of Leukocyte Biology. – 2020. – V. 107. – No 6. – P. 933–939.
Kolesnikova, E.A. The genome structure of ciprofloxacin-resistant Mycoplasma hominis clinical isolates / E.A. Kolesnikova, N.F. Brusnigina, M.A. Makhova, A.E. Alekseeva // Acta Naturae (англоязычная версия). – 2020. – V. 12. – No 1 (44). – P. 56–62.
Mocroft, A. Influence of Hepatitis C Coinfection and Treatment on Risk of Diabetes Mellitus in HIV-Positive Persons / A. Mocroft, J. D. Lundgren, J. K. Rockstroh, et al. // Open forum infectious diseases. – 2020. – V. 7. – No ‏12. – ofaa470.
Morozova, O.V. Phylodynamics of G4P[8] and G2P[4] strains of rotavirus A isolated in Russia in 2017 based on full-genome analyses / O.V. Morozova, T.A. Sashina, N.V. Epifanova, et al. // Virus Genes. – 2020. – V. 56. – No 5. – P. 537–545.
Neumoina, N. V. Genetic variants of H.pylori in different forms of chronic gastritis / N.V. Neumoina, E.I. Efimov, K.M. Perfilova, I.V. Shutova, M.V. Neumoina, T.A. Troshina, T.Yu. Butina, I.V. Kuznetsova, M.A. Semaka // Opera Med Physiol. 2020. Vol.7 (3). P. 17 – 27.
Novikova, N.A. Long-term monitoring of G1P[8] rotaviruses circulating without vaccine pressure in Nizhny Novgorod, Russia, 1984–2019 / N.A. Novikova, T.A. Sashina, N.V. Epifanova, et al. // Archives of Virology. – 2020. – Т. 165. – № 4. – С. 865–875.
Sashina, T.A. Genotype constellations of the rotavirus A strains circulating in Nizhny Novgorod, Russia, 2017–2018 / T.A. Sashina, O.V. Morozova, N.V. Epifanova, N.A. Novikova // Infection, Genetics and Evolution. – 2020. – V. 85. – P. 104578.
Talayev, V. Low-dose influenza vaccine grippol quadrivalent with adjuvant polyoxidonium induces a T helper-2 mediated humoral immune response and increases NK cell activity // V. Talayev, I. Zaichenko., M. Svetlova., et al. // Vaccine. – 2020. – V. 38. – No 42. – P. 6645–6655.
Vasilenko, E.A. The structure of myeloid cell-specific TNF inhibitors affects their biological properties / E.A. Vasilenko, E.N. Gorshkova, I.V. Astrakhantseva, et al. // FEBS Letters. – 2020. – V. 594. – No 21. – P. 3542–3550.

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